Scientific Publications by FDA Staff
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J Chromatogr B 2016 Jun 1;1022:183-90
Iodine speciation in dog foods and treats by high performance liquid chromatography with inductively coupled plasma mass spectrometry detection.
Wilson RA, Yanes EG, Kemppainen RJ
Abstract
An analytical method for determination of the iodine species 3-monoiodotyrosine (MIT), iodide, 3,5-diiodotyrosine (DIT), 3,5-diiodothyronine (3, 5-T2), 3,5,3'-triiodothyronine (T3), and thyroxine (T4) in dog foods and treats is reported. Iodine speciation was carried out using a HPLC method capable of both anion-exchange and reversed-phase retention coupled with inductively coupled plasma mass spectrometry detection (LC-ICP-MS). The method was evaluated by the analysis of the iodine species concentrations in twelve dog foods and treats following enzymatic digestion. The concentrations of MIT, iodide, DIT, T3, and T4 in the samples ranged from 0.64-59.5mug/g, 0.86-4.05mug/g,
Category:
Journal Article
PubMed ID:
#27107244
DOI:
10.1016/j.jchromb.2016.04.002
Includes FDA Authors from Scientific Area(s):
Regulatory Affairs
Entry Created:
2016-04-24