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U.S. Department of Health and Human Services

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Title:  Oxolinic acid in the trout: bioavailability and tissue residues.
 
Authors:  Archimbault P, Ambroggi G, Nicolas S
 
Drug:  Oxolinic acid
 
Fish species:  Trout, rainbow
 
Date:  1988
 
t1/2-hr:  96
 
est:  est
 
Sample:  muscle+skin
 
Ave Weight (gm):  200
 
Ave Water temp (°C):  10
 
Water:  Freshwater
 
Dosage:  12 mg/kg 7 d
 
Route:  PO
 
Comments:  Recommend 6 d withdrawal time to be below 0.05 ppm. Residue during treatemen clustered around 1.4 ug/g. Residues post treatement 24 h=1.9, 48h=0.9, 96h=0.09, 144h=0.05, 240h =0.03 ug/g.
 
Citation:  Annales de Recherches Veterinaires 19:39-43
 
Dep-time:  6 d
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3400972&dopt=Abstract  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  48 h
 
Wt gm-detail:  200 g
 
Water temp (°C)-detail:  9-10 C
 
Dosage-detail:  12 mg/kg 7 d
 
Method:  HPLC
 
Authors-red:  Archimbault P, Ambroggi G, Nicolas S
 
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