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U.S. Department of Health and Human Services

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Title:  Orally administered erythromycin in Rainbow trout (Oncorhynchus mykiss): Residues in the edible tissues and withdrawal time.
 
Authors:  Esposito A, Fabrizi L, Lucchetti D, Marvasi L, Coni E, Guandalini E
 
Drug:  Erythromycin
 
Fish species:  Trout, rainbow
 
Date:  2007
 
t1/2-hr:  48
 
est:  est
 
Sample:  muscle+skin
 
Ave Weight (gm):  200
 
Ave Water temp (°C):  11
 
Water:  Freshwater
 
Dosage:  100 mg/kg 21d
 
Route:  PO
 
Comments:  Residue: day:(DegreeDay)=mg/kg 0.13d(1.4=45, 0.5d(5.75)=50, 1d(11.5)=35, 2d(23)=18, 4d(46)=7, 7d(81)=0.6, 10d(115)=0.3, 20d(230)=0.1, 30d(345=0.07. withdrawl time about 22 d in 10-12 deg water.
 
Citation:  Antimicrobial Agents and Chemotherapy 51:1043-7
 
Dep-time:  255 degreedays
 
Link:  http://aac.asm.org/cgi/content/abstract/AAC.01002-06v1  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Macrolide
 
t1/2-detail:  48 h est
 
Wt gm-detail:  200 +/-11g
 
Water temp (°C)-detail:  11 +/- 0.5 C
 
Dosage-detail:  10 mg/kg 21 d
 
Method:  HPLC
 
Authors-red:  Esposito A, Fabrizi L, Lucchetti D, Marvasi L, Coni E, Guandalini E
 
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