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Title:
Pharmacokinetics of sulphamonomethoxine and sulphadimethoxine following oral administration to cultured rainbow trout (Oncorhynchus mykiss).
Authors:
Uno K, Aoki T, Ueno R (1993b)
Drug:
Sulfadimethoxine
Fish species:
Trout, rainbow
Date:
1993
t1/2-hr:
60
Sample:
intestinal tract-bile
Ave Weight (gm):
240
Ave Water temp (°C):
15
Water:
Freshwater
Dosage:
200 mg/kg sd
Route:
PO
Comments:
Residue ug/g max 3d=1771, 0.5h=nd, 1h=nd, 3h=0.61, 6h=7.25, 9h=20.1, 12h=28.0, 24h=1079?, 2d=1179, 3d=1771, 5d=3.55, 7d=2.58, 10d=nd, 13d=0.13, 16d=nd, 20d=0.17, 24d=0.17, 28d=3.47, 32d=nd.
Metabolites:
N4-A-SDM
Citation:
Aquaculture 115:209-219
Dep-time:
30 days
Link:
http://dx.doi.org/10.1016/0044-8486(93)90137-N
Genus Species:
Oncorhynchus mykiss
Drug Class:
Antibiotic-Sulfa
t1/2-detail:
59.4 h
Wt gm-detail:
210-270 g
Water temp (°C)-detail:
15 C
Dosage-detail:
200 mg/kg sd
Method:
HPLC
Authors-red:
Uno K, Aoki T, Ueno R (1993b)
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