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U.S. Department of Health and Human Services

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Title:  Oxytetracycline depletion from skin-on fillet tissue of coho salmon fed oxytetracycline medicated feed in freshwater at temperatures less than 9°C.
 
Authors:  Meinertz JR, Gaikowski MP, Stehly GR, Gingerich WH, Evered JA
 
Drug:  Oxytetracycline
 
Fish species:  Salmon, coho
 
Date:  2001
 
t1/2-hr:  118
 
Sample:  muscle+skin+scales
 
Ave Weight (gm):  38
 
Ave Water temp (°C):  9
 
Water:  Freshwater
 
Dosage:  88.2 mg/kg, divided BID 10 d
 
Route:  PO
 
Comments:  Mean concentrations: Treatment day 4=563, Treatment day 10 = 810, Depletion days: 1 = 932, d4=330, d8=150, d14=60, d19=32 ng/g. (Toleance for OTC = 2000 ng/g).
 
Citation:  Aquaculture 198: 29-39
 
Link:  http://dx.doi.org/10.1016/S0044-8486(01)00512-9  Opens a new window
 
Genus Species:  Oncorhynchus kisutch
 
Drug Class:  Antibiotic-Tetracycline
 
t1/2-detail:  4.9 d
 
Wt gm-detail:  13-62 g
 
Water temp (°C)-detail:  4.1-8.5 C
 
Dosage-detail:  88.2 mg/kg, divided BID for 10 d
 
Method:  HPLC
 
Authors-red:  Meinertz JR, Gaikowski MP, Stehly GR, Gingerich WH, Evered JA
 
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