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Title:
Florfenicol residue depletion in channel catfish, Ictalurus punctatus (Rafinesque).
Authors:
Wrzesinski C, Crouch L, Gaunt P, Holifield D, Bertrand N, Endris D.
Drug:
Florfenicol
Fish species:
Catfish, channel
Date:
2006
t1/2-hr:
48
est:
est
Sample:
muscle
Ave Weight (gm):
920
Ave Water temp (°C):
19
Water:
Freshwater
Dosage:
10 mg/kg 10 d*
Route:
PO
Comments:
Dose: fish fed poorly for first two days so the dose was fed for 12 days. Expected dose based on feed consumption 9.3 mg/kg/day for the last 10 days. Residues in male and female fish similar. Mean Residues (ppb) [median in brackets] withdrawal d1=5378 [2684], d2=2303 [831], d4=876 [702], d7=232 [185], d14=168 [142], d21=169 [151]. Samples below LOQ or LOD were not used in calculating average.
Metabolites:
Florfenicol amine
Citation:
Aquaculture 253:309-316
Link:
http://dx.doi.org/10.1016/j.aquaculture.2005.05.005
Genus Species:
Ictalurus punctatus
Drug Class:
Antibiotic-Phenicol
t1/2-detail:
48 h est
Wt gm-detail:
2.02 llb
Water temp (°C)-detail:
ave 20.7C Rx, ave 17.9C WD
Dosage-detail:
10 mg/kg 10 d*
Method:
HPLC-UV
Authors-red:
Wrzesinski C, Crouch L, Gaunt P, Holifield D, Bertrand N, Endris D.
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