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Title:
Pharmacokinetics of oxytetracycline in black tiger shrimp, Penaeus monodon, and the effect of cooking on the residues.
Authors:
Uno K, Aoki T, Kleechaya W, Tanasomwang V, Ruangpan L.
Drug:
Oxytetracycline
Fish species:
Shrimp, giant tiger prawn (black tiger)
Date:
2006
t1/2-hr:
16
Sample:
blood, hemolymph
Ave Weight (gm):
23
Ave Water temp (°C):
30
Water:
Brackish
Dosage:
10 mg/kg sd
Route:
IS
Comments:
AUC=258 t1/2 alpha=0.2h, beta = 16.2 h. Residues from graph ug/ml, wd 0.5d=5, 1d=3, 2d=1, 3d=0.3, 4d=0.11, 5d=0.1. Vss=869 ml/kg
Cl:
38.7mg/kg/h
Vc:
217 ml/kg
Vd:
869 ml/kg
Citation:
Aquaculture 254:24-31
Link:
http://dx.doi.org/10.1016/j.aquaculture.2005.10.031
Genus Species:
Penaeus monodon
Drug Class:
Antibiotic-Tetracycline
t1/2-detail:
alpha=0.20h, beta=16.2 h
Wt gm-detail:
22.9+/-4.9g
Water temp (°C)-detail:
29-30 C
Dosage-detail:
10 mg/kg sd
Method:
HPLC
Authors-red:
Uno K, Aoki T, Kleechaya W, Tanasomwang V, Ruangpan L.
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