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U.S. Department of Health and Human Services

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Title:  Pharmacokinetics of oxytetracycline in black tiger shrimp, Penaeus monodon, and the effect of cooking on the residues.
 
Authors:  Uno K, Aoki T, Kleechaya W, Tanasomwang V, Ruangpan L.
 
Drug:  Oxytetracycline
 
Fish species:  Shrimp, giant tiger prawn (black tiger)
 
Date:  2006
 
t1/2-hr:  16
 
Sample:  blood, hemolymph
 
Ave Weight (gm):  23
 
Ave Water temp (°C):  30
 
Water:  Brackish
 
Dosage:  50 mg/kg sd
 
Route:  PO
 
Comments:  AUC= ug h/ml=459, MRT h=27.2, C max ug/ml=21.1, tmax 4h. Bioaval=35.6. Residues from graph ug/ml, wd 0.5d=11, 1d=8, 2d=5, 3d=1, 4d=0.2, 5d=0.08.
 
Protein binding:  49
 
Citation:  Aquaculture 254:24-31
 
Link:  http://dx.doi.org/10.1016/j.aquaculture.2005.10.031  Opens a new window
 
Genus Species:  Penaeus monodon
 
Drug Class:  Antibiotic-Tetracycline
 
t1/2-detail:  16.4 h
 
Wt gm-detail:  22.9+/-4.9g
 
Water temp (°C)-detail:  29-30 C
 
Dosage-detail:  50 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Uno K, Aoki T, Kleechaya W, Tanasomwang V, Ruangpan L.
 
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