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Title:
Effect of dose escalation on multiple dose pharmacokinetics of orally administered praziquantel in kingfish Seriola lalandi.
Authors:
Tubbs L, Tingle M
Drug:
Praziquantel
Fish species:
Amberjack, yellowtail (kingfish)
Date:
2006
t1/2-hr:
24
est:
est
Sample:
skin
Ave Weight (gm):
500
Ave Water temp (°C):
19
Water:
Saltwater
Dosage:
50 mg/kg 8 d*
Route:
PO
Comments:
Oral intubation in DMSO solution- New Zealand recommended dose. Compare with hi dose. Max conc 4-5 ug/g, min approx 1 every 24 hr. t 1/2 est from graph.
Citation:
Aquaculture 261:1168-1174
Link:
http://dx.doi.org/10.1016/j.aquaculture.2006.09.013
Genus Species:
Seriola lalandi
Drug Class:
Antiparasitic-Praziquantel
t1/2-detail:
24 est
Wt gm-detail:
400-600 g
Water temp (°C)-detail:
18-19 C
Dosage-detail:
50 mg/kg 8 d*
Method:
HPLC
Authors-red:
Tubbs L, Tingle M.
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