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U.S. Department of Health and Human Services

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Title:  Bioavailability of oxolinic acid in Atlantic salmon (Salmo salar L.) from medicated feed.
 
Authors:  Hustvedt SO, Salte R, Kvendset O, Vassvik V
 
Drug:  Oxolinic acid
 
Fish species:  Salmon, Atlantic
 
Date:  1991
 
t1/2-hr:  28
 
Sample:  blood, serum
 
Ave Weight (gm):  1108
 
Ave Water temp (°C):  9
 
Water:  Saltwater
 
Dosage:  9 mg/kg sd
 
Route:  PO
 
Comments:  Bioavailability=21%. Mean serum concentrations ug/ml after oral dose 6h=1.34, 9h=1.66, 12=1.64, 24h=1.17, 48h=0.73, 96h=0.22, 144h=0.04, 192h=0.03, 240h=0.01. Cmax= 1.7 mg/ml at 10.8 h. Salinity 25%.
 
Citation:  Aquaculture 97:305-310
 
Link:  http://dx.doi.org/10.1016/0044-8486(91)90322-X  Opens a new window
 
Genus Species:  Salmo salar
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  20-37.4 h
 
Wt gm-detail:  1108+/-135 g
 
Water temp (°C)-detail:  9 C
 
Dosage-detail:  9 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Hustvedt SO, Salte R, Kvendset O, Vassvik V
 
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