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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Disposition of flumequine in plasma of European eel (Anguilla anguilla) after a single intramuscular injection.
 
Authors:  Boon JH, Nouws JMF, van der Heijden MHT, Booms GHR, Degen M
 
Drug:  Flumequine
 
Fish species:  Eel, European
 
Date:  1991
 
t1/2-hr:  255
 
Sample:  blood, plasma
 
Ave Weight (gm):  488
 
Ave Water temp (°C):  23
 
Water:  Freshwater
 
Dosage:  9 mg/kg sd
 
Route:  IM
 
Comments:  Peak between 48-96 hrs - 8.97 & 8.84 ug/ml. Absorption t 1/2 = 33.2, Alpha t 1/2 = 70.8. By 1056 hrs 86.6 % of dose was recovered from aquarium water.
 
Protein binding:  30-40%
 
Cl:  0.0035 L/kg/h
 
Citation:  Aquaculture 99: 213-223
 
Link:  http://dx.doi.org/10.1016/0044-8486(91)90242-Y  Opens a new window
 
Genus Species:  Anguilla anguilla
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  255 h
 
Wt gm-detail:  377.9-647.0 g
 
Water temp (°C)-detail:  25 C, 22 C between replacements
 
Dosage-detail:  9 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Boon JH, Nouws JMF, van der Heijden MHT, Booms GHR, Degen M
 
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