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Title:
Pharmacokinetics and bioavailabilities of 14C-ketocarotenoides, astaxanthin and canthaxanthin, in rainbow trout, Oncorhynchus mykiss.
Authors:
Choubert G, Cravedi J-P, Laurentile M
Drug:
Canthaxanthin
Fish species:
Trout, rainbow
Date:
2005
t1/2-hr:
6
Sample:
blood
Ave Weight (gm):
1000
Ave Water temp (°C):
17
Water:
Freshwater
Dosage:
0.24 mg/kg sd
Route:
IVC
Comments:
Canthaxanthin-14C, AUC 42.09 ugeq/ml. Urine contained < 0.5% radioactivity over 48h. Biliary excretion 3.6%. Aorta and urinary catheterized fish.
Cl:
17.3
Vd:
208
Citation:
Aquaculture Research 36:1526-1534
Link:
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2109.2005.01375.x
Genus Species:
Oncorhynchus mykiss
Drug Class:
Organic-Carotenoid
t1/2-detail:
6.02 h
Wt gm-detail:
1 kg
Water temp (°C)-detail:
17 +/- 1C
Dosage-detail:
836.2 kBq/Kg, 0.24 mg/kg
Method:
Rad
Authors-red:
Choubert G, Cravedi J-P, Laurentile M
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