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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Uptake, distribution, metabolism and clearance of chlordecone by channel catfish (Ictalurus punctatus).
 
Authors:  Van Veld PA, Bender ME, Roberts MH
 
Drug:  Chlordecone
 
Fish species:  Catfish, channel
 
Date:  1984
 
t1/2-hr:  209
 
Sample:  whole body-gutted
 
Ave Weight (gm):  7
 
Ave Water temp (°C):  19
 
Water:  Freshwater
 
Dosage:  0.027 ng/mg 90d
 
Route:  PO
 
Comments:  Dose 0.027 ng/mg for 90d- * "the half life of chlordecone in these fish was 8.7 d"; the clearance rate constant was 0.080/day (wet wt basis), Chlordecone (14C), Dechlorane, and chlordecone also known as Kepone
 
Metabolites:  Chlordecone alcohol
 
Citation:  Aquatic Toxicology 5:33-49
 
Link:  http://dx.doi.org/10.1016/0166-445X(84)90030-4   Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Organic-Chlorinated-Pesticide
 
t1/2-detail:  8.7 d *
 
Wt gm-detail:  6.5 +/- 0.25 g
 
Water temp (°C)-detail:  19 +/- 1 C
 
Dosage-detail:  0.027 ng/mg for 90d
 
Method:  GC, Rad
 
Authors-red:  Van Veld PA, Bender ME, Roberts MH
 
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