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U.S. Department of Health and Human Services

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Title:  Gastrointestinal uptake of cadmium and zinc by a marine teleost Acanthopagrus schlegeli.
 
Authors:  Zhang L, Wang WX
 
Drug:  Cadmium
 
Fish species:  Seabream, blackhead
 
Date:  2007
 
Sample:  intestinal tract-intestine
 
Ave Weight (gm):  10
 
Ave Water temp (°C):  25
 
Water:  Saltwater
 
Dosage:  5.7 nM 4h
 
Route:  BATH
 
Comments:  [109]Cd. Seawater-35 ppt, weight = dry weight. Dose given by gavage under MS222. %of body accumulation= 66-90%- increased over 7 days. After 4h, 43% of Cd distributed in the intestine. Retained about 10-20% of Cd from perfusion medium. Uptake kinetics were determined as a first-order absorption pattern over a range (6.2nM-4.5uM) of ambient metal concentrations. Positive correlation between Cd concentration and uptake rate. Uptake rate constant 28.2 nmol/g/d. Kinetic order 0.818.
 
Citation:  Aquatic Toxicology 85:143-153
 
Link:  http://dx.doi.org/10.1016/j.aquatox.2007.08.008  Opens a new window
 
Genus Species:  Acanthopagrus schlegelii schlegelii
 
Drug Class:  Metal-Cadmium
 
Wt gm-detail:  10.1+/- 2.4 g dry weight
 
Water temp (°C)-detail:  25 C
 
Dosage-detail:  5.7 nM 4h-7d
 
Method:  Rad
 
Authors-red:  Zhang L, Wang WX
 
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