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U.S. Department of Health and Human Services

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Title:  Uptake and enantioselective elimination of chlordane compounds by common carp (Cyprinus carpio, L.).
 
Authors:  Seemamahannop R, Berthod A, Maples M, Kapila S, Armstrong DW
 
Drug:  Chlordane
 
Fish species:  Carp, common
 
Date:  2005
 
t1/2-hr:  478
 
Sample:  whole body
 
Ave Weight (gm):  0.8
 
Water:  Freshwater
 
Dosage:  5 ppb (5ng/g)* 3d
 
Route:  BATH
 
Comments:  Chlordane uptake is not enantioselective. During depuration- global trans chlordane t1/2=408h, (-)trans chlordane t1/2= 355h, (+) chlordane=478h, cis-chlordane=433h. K2=0.00145/h. Max residue approx 310 ng/g, dpeuration 200h=210, 400h=130, 1200h=30.
 
Metabolites:  trans-chlordane (+)
 
Citation:  Chemosphere 59:493-500
 
Dep-time:  85% gone by 50 d
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15788172&query_hl=1  Opens a new window
 
Genus Species:  Cyprinus carpio
 
Drug Class:  Organic-Chlorinated-Pesticide
 
t1/2-detail:  20 d
 
Wt gm-detail:  0.6-1g (initial), 2-3 g (end)
 
Water temp (°C)-detail:  not specified
 
Dosage-detail:  5 ppb (5ng/g)* 3d
 
Method:  GC/MS, 2D
 
Authors-red:  Seemamahannop R, Berthod A, Maples M, Kapila S, Armstrong DW
 
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