Quantitative analysis of alterations in liver ultrastructure of rainbow trout Oncorhynchus mykiss after administration of the aquaculture antibacterials oxolinic acid and flumequine.
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Moutou KA, Braunbeck T, Houlihan DF
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Oxolinic acid
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Trout, rainbow
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1997
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liver
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0
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0
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Freshwater
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1.0 g/kg 10 d
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PO
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Ultrastructure of liver showed 2.5 increase in volume of rough endoplasmic reticulum - dilation, vesiculation and fragmentation. Bycogen deposits were depleted by 50%. Intralysosomal accumulation of stacked membranes and myelin figures in cytoplasm. Mitochondiral hyperplasia.
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Diseases of Aquatic Organisms 29:21-34 Abstract
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http://www.int-res.com/abstracts/dao/v29/n1/p21-34/
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Oncorhynchus mykiss
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Antibiotic-Quinolone
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Not specified
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Not specified
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1.0 g/kg 10 d
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Rad
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Moutou KA, Braunbeck T, Houlihan DF
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