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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Pharmacokinetics of flumequine and in vitro activity against bacterial pathogens of gilthead sea bream Sparus aurata.
 
Authors:  Rigos G, Trypenou AE, Nengas I, Yiagnisis M, Koutsodimou M, Alexis M, Troisi GM
 
Drug:  Flumequine
 
Fish species:  Seabream, gilthead
 
Date:  2003
 
t1/2-hr:  30
 
Sample:  blood, plasma
 
Ave Weight (gm):  170
 
Ave Water temp (°C):  19
 
Water:  Saltwater
 
Dosage:  10 mg/kg sd
 
Route:  IV
 
Comments:  AUC 119.59 ug.hr/ml
 
Cl:  0.05 L/kg/h
 
Vc:  0.15 L/kg
 
Vd:  0.57 L/kg
 
Citation:  Diseases of Aquatic Organisms 54:35-41
 
Link:  http://www.int-res.com/articles/dao2003/54/d054p035.pdf  Opens a new window
 
Genus Species:  Sparus aurata
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  30 hr
 
Wt gm-detail:  170 g
 
Water temp (°C)-detail:  19+/-0.05 C
 
Dosage-detail:  10 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Rigos G, Trypenou AE, Nengas I, Yiagnisis M, Koutsodimou M, Alexis M, Troisi GM
 
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