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U.S. Department of Health and Human Services

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Title:  Bioconcentration and elimination of avermectin B1 in sturgeon.
 
Authors:  Shen J, Zhang Q, Ding S, Zhang S, Coats JR
 
Drug:  Avermectin B1
 
Fish species:  Sturgeon
 
Date:  2005
 
t1/2-hr:  119
 
Sample:  muscle
 
Ave Weight (gm):  36
 
Ave Water temp (°C):  20
 
Water:  Freshwater
 
Dosage:  0.2 ng/ml 22d
 
Route:  BATH
 
Comments:  Residue 7.75 +/- 0.88ng/g d22..Withdrawal d 18=1.91 +/-0.37 ng/g. d40=ND The estimated value of bioconcentration factor was 42 L/kg, utake constant=5.9, elim constant =0.14, Average recoveries of fortified water samples were 80.5% +/- 5.1% for 1 ng/mL, 83.7% +/- 3.8% for 4 ng/mL, and 89.1 +/- 4.0% for 7 ng/mL.
 
Citation:  Environmental Toxicology and Chemistry 24: 396-399
 
Link:  http://www.ncbi.nlm.nih.gov/pubmed/15720000?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum  Opens a new window
 
Genus Species:  Acipenser sp
 
Drug Class:  Antiparasitic-Avermectin
 
t1/2-detail:  119 h
 
Wt gm-detail:  35.8+/-4.6g
 
Water temp (°C)-detail:  20+/-1 C
 
Dosage-detail:  Flow through 0.2 ng/ml for 22 days.
 
Method:  HPLC
 
Authors-red:  Shen J, Zhang Q, Ding S, Zhang S, Coats JR
 
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