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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Total residue depletion and metabolic profile of selected drugs in salmonids: Acriflavine and Proflavine.
 
Authors:  Hayton WL (1997d)
 
Drug:  Acriflavine
 
Fish species:  Trout, rainbow
 
Date:  1997
 
Sample:  skin
 
Ave Weight (gm):  443
 
Ave Water temp (°C):  12
 
Water:  Freshwater
 
Dosage:  4 mg/l 4 hr
 
Route:  BATH
 
Comments:  Only measured residues in skin every 8 days. Day 0 = 383 ppb. Day 8 had 126 ppb (32.9%) of the radioactivity that was measured for day 0. Day 16 had 94 ppb (24.6) of the radioactivity that was measured for day 0. Acriflavine (14C)
 
Vd:  31.2 L/kg
 
Metabolites:  Unidentified metabolites
 
Citation:  Final FDA Report. Contract 223-93-7014. Vol 1. Study 728363-008.
 
Link:  none  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Organic-Dye
 
Wt gm-detail:  443 +/- 35.5 g
 
Water temp (°C)-detail:  12 C
 
Dosage-detail:  4 ppm 4 hr
 
Method:  HPLC-Rad
 
Authors-red:  Hayton WL (1997b)
 
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