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Title:
Total residue depletion and metabolic profile of selected drugs in salmonids: 17±-Methyltestosterone.
Authors:
Hayton WL (1997c)
Drug:
Methyltestosterone
Fish species:
Trout, rainbow
Date:
1997
t1/2-hr:
19
Sample:
blood, plasma
Ave Weight (gm):
427
Ave Water temp (°C):
12
Water:
Freshwater
Dosage:
37.6 µCi (.25 mg)
Route:
IVC
Comments:
Only one fish was used; Vd= 1.86 L/kg; Vc= 1.45 L/kg, log-linear= 18.7 h distribution= 2.5 h. Residues (ppb) 72 hr after IV dose = 14.9.
Cl:
0.39 L/kg/h
Vc:
1.45 L/kg
Vd:
1.86 L/kg
Citation:
Final FDA Report. Contract 223-93-7014. Vol 2.
Link:
none
Genus Species:
Oncorhynchus mykiss
Drug Class:
Hormone-Testosterone
t1/2-detail:
log-linear= 18.7 hdistribution= 2.5 h
Wt gm-detail:
427 g
Water temp (°C)-detail:
12 C
Dosage-detail:
37.6 µCi (.25 mg)
Method:
HPLC-Rad
Authors-red:
Hayton WL (1997c)
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