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Title:
Depletion of oxytetracycline from subadult penaeid shrimp: Analytical Chemistry.
Authors:
Carson MC, Ngoh MA, Kijak PJ, Heller DN, Williams RR
Drug:
Oxytetracycline
Fish species:
Shrimp, whiteleg
Date:
1998
t1/2-hr:
13
Sample:
muscle
Ave Weight (gm):
11
Water:
Freshwater
Dosage:
22.5 mg/kg BID 14 d
Route:
PO
Comments:
PO in feed - nominal 4.5 g/kg feed, actual measured conc 3.24 g/kg feed. Shrimp were approx 11 g and fed 6-10%BWT. Residues ppm wd = 0h=3.85, 12 h=2.99, 24 h=1.83, 36h=1.50, 48h=0.28, 72h <0.25 (LOQ) - most estimated <0.1. t1/2 estimated by authors - initial = 21 hrs, terminal 10 hrs, overall about 13 hrs.
Citation:
Final FDA Report. Study 333.01
Link:
none
Genus Species:
Litopenaeus vannamei
Drug Class:
Antibiotic-Tetracycline
t1/2-detail:
initial=21h, terminal =10h, overal=13h
Wt gm-detail:
> 11 g
Water temp (°C)-detail:
Texas ponds in August 1998
Dosage-detail:
22.5 mg/kg BID 14 d (6-10% BW divided BID of 4.5 g/kg feed
Method:
HPLC
Authors-red:
Carson MC, Ngoh MA, Kijak PJ, Heller DN, Williams RR
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