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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  The metabolic clearance rate of estradiol-17b in rainbow trout, Salmo gairdneri R., estimated by both single injection and constant infusion methods: Increase during oocyte maturation.
 
Authors:  Baroiller JF, Foster A, Zohar Y, Marcuzzi O
 
Drug:  Estradiol-17²
 
Fish species:  Trout, rainbow
 
Date:  1987
 
Sample:  blood, plasma
 
Ave Weight (gm):  1650
 
Ave Water temp (°C):  12
 
Water:  Freshwater
 
Dosage:  2-7 µCi/kg sd
 
Route:  IVC
 
Comments:  MCR at beginning of exogenous vitellogenesis= 23.1-34.8 ml/kg/hr, MCR at advanced exogenous vitellogenesis stages= 18.5-23.8 ml/kg/hr, MCR during 1st stages of oocyte maturation= 32.8-45.2 ml/kg/hr, Estradiol-17² ([2,4,6,7-3H]E2-17²)
 
Citation:  General and Comparative Endocrinology 66: 85-94
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3582947&dopt=Abstract  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Hormone-Estrogen
 
Wt gm-detail:  1.3-2 kg
 
Water temp (°C)-detail:  12 +/- 2 C
 
Dosage-detail:  2-7µCi/kg sd
 
Method:  Rad
 
Authors-red:  Baroiller JF, Foster A, Zohar Y, Marcuzzi O
 
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