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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Uptake, metabolism, and elimination of niclosamide by fish.
 
Authors:  Dawson VK, Schreier TM, Boogaard MA, Gingerich WH
 
Drug:  Niclosamide-(2,5-Dichloro-4-nitrosalicylanilide)
 
Fish species:  Trout, rainbow
 
Date:  1999
 
Sample:  viscera
 
Ave Weight (gm):  0
 
Ave Water temp (°C):  0
 
Water:  Freshwater
 
Dosage:  0.005 mg/L 35d
 
Route:  BATH
 
Comments:  (14C)-niclosamide. Unpublished data by Hubert et al. Seven fish sampled on exposure days 0, 3, 7, 14, 21, 28, 31, and 35. Radioactive residues rapidly accumulated during first 3 days of exposure. Bioconcentration factor for whole body=215. Average equilibrium bioconcentration factor=916 for viscera. 80% of niclosamide residues in viscera.
 
Citation:  In: D.J. Smith, W.H. Gingerich and M.G. Beconi-Barker (Eds.). Xenobiotics in Fish. Kluwer Academic/Plenum Publishers. pp. 167-176.
 
Link:  none  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antiparasitic-Niclosamide
 
Wt gm-detail:  Not Specified
 
Water temp (°C)-detail:  Not Specified
 
Dosage-detail:  0.005 mg/L 35d
 
Method:  Rad
 
Authors-red:  Dawson VK, Schreier TM, Boogaard MA, Gingerich WH
 
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