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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Uptake, metabolism and elimination of TFM in fish.
 
Authors:  Hubert TD, Bernardy JA, Vue C, Gingerich WH
 
Drug:  TFM-(3-Trifluoromethyl-4-nitrophenol)
 
Fish species:  Trout, rainbow
 
Date:  1999
 
Sample:  muscle+skin
 
Ave Weight (gm):  2
 
Ave Water temp (°C):  0
 
Water:  Freshwater
 
Dosage:  62 ug/L flow through
 
Route:  BATH
 
Comments:  Unpublished data by Hubert et al. (14C)TFM. Levels reached a steady state at d3 lasting till day 28, then levels changed. Residue 24h=0.05 ug/g. TFM residue at 504h exposure=0.006 ug/g. TFM-Glu residue at 504h exposure=0.036 ug/g.
 
Metabolites:  Glucuronide
 
Citation:  In: D.J. Smith, W.H. Gingerich and M.G. Beconi-Barker (Eds.). Xenobiotics in Fish. Kluwer Academic/Plenum Publishers. pp. 177-187
 
Link:  none  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Organic-Phenol
 
Wt gm-detail:  2 g
 
Water temp (°C)-detail:  Not Specified
 
Dosage-detail:  62 ug/L 28d
 
Method:  HPLC-Rad
 
Authors-red:  Hubert TD, Bernardy JA, Vue C, Gingerich WH
 
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