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U.S. Department of Health and Human Services

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Title:  Residues of MS-222, benzocaine and their metabolites in striped bass following anesthesia.
 
Authors:  Luhning CW
 
Drug:  Benzocaine
 
Fish species:  Bass, striped
 
Date:  1973
 
t1/2-hr:  1
 
est:  est
 
Sample:  whole body-minus head, scales, viscera, fins
 
Ave Weight (gm):  55
 
Ave Water temp (°C):  18
 
Water:  Freshwater
 
Dosage:  63.2 mg/l 15 min
 
Route:  BATH
 
Comments:  t1/2 est. from chart. Mean Residue of free benzocaine residue (ug/g) in the muscle was at withdrawal time 0h= 37.9, 1 h=7.3, 4 h=0.7, 24 h=0.2. Free p-aminobenzoic acid residue at withdrawal time 0h=1.5, 1h=0.2, 4h= 0.1, 24 h=0.0. Levels dropped significantly after storage of samples for 1 week at 1.7 C.
 
Metabolites:  p-aminobenzoic acid
 
Citation:  Investigations in Fish Control. U.S. Dept. of the Interior, Fish and Wildlife Service, Bureau of Sport Fisheries and Wildlife. SH157.7.I58 no.52
 
Link:  none  Opens a new window
 
Genus Species:  Morone saxatilis
 
Drug Class:  Anesthetic-Benzocaine
 
t1/2-detail:  <1 h
 
Wt gm-detail:  54.5 g
 
Water temp (°C)-detail:  18 +/- 0.5 C
 
Dosage-detail:  63.2 mg/l 15 min
 
Method:  Absorbance-Bratton&Marshall, TLC
 
Authors-red:  Luhning CW
 
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