Quick Links: Skip to main page content Skip to Search Skip to Topics Menu Skip to Common Links
  • Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

PhishPharm - Detail
  • Print
  • Share
  • E-mail
-
 
Title:  Evaluation of a method of intracoelomic catheterization in koi.
 
Authors:  Lewbart G, Butkus D, Papich M, Coleman A, Krum H, Noga E
 
Drug:  Enrofloxacin
 
Fish species:  Carp, common (koi)
 
Date:  2005
 
t1/2-hr:  71
 
Sample:  blood, plasma
 
Ave Weight (gm):  613
 
Ave Water temp (°C):  19
 
Water:  Freshwater
 
Dosage:  10 mg/kg sd
 
Route:  IP
 
Comments:  Cipro metabolite not found. Cmax = 4.72 g/mL (at 12 hours) Concentrations from graph: 2h = 4.5, 4h = 4, 8h = 4, 12h = 4.5, 24h = 3.5, 48h = 3.3, 72h = 2.5. Elimination rate = 0.0098 L/h, Tmax = 12 h, AUC = 501.84 h g/mL, Vd/F reported = 1012.7 mL/kg, Cl reported = 9.96 ml/h/kg, AUMC = 52,118 h^2g/mL, MRT = 103.9 h. study compares IP with Intracoelomic Catheter.
 
Cl:  0.01
 
Vd:  1.012
 
Metabolites:  Ciprofloxacin
 
Citation:  J American Veterinary Medical Association 226:784-788
 
Link:  http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=15776954&ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum  Opens a new window
 
Genus Species:  Cyprinus carpio
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  70.4551 h
 
Wt gm-detail:  212-1014 g
 
Water temp (°C)-detail:  18.5-19.5 C
 
Dosage-detail:  10 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Lewbart G, Butkus D, Papich M, Coleman A, Krum H, Noga E
 
-
-