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U.S. Department of Health and Human Services

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Title:  Astaxanthin and Canthaxanthin kinetics after ingestion of individual doses by immature rainbow trout Oncorhynchus mykiss.
 
Authors:  Gobantes I, Choubert G, Laurentie M, Milicua JCG, Gomez R
 
Drug:  Astaxanthin
 
Fish species:  Trout, rainbow
 
Date:  1997
 
t1/2-hr:  35
 
Sample:  blood, serum
 
Ave Weight (gm):  300
 
Ave Water temp (°C):  20
 
Water:  Freshwater
 
Dosage:  100 ug sd
 
Route:  PO
 
Comments:  Of 234 fish dosed, 4 did not show a serum response to carotenoid pigments. Max 4.4 nmol/ml 18 h post dose. Residue at 50% at 48 h, 30% at 72 h. Mean retention time = 56.4 h. Large variations in individual animals. AUC 157.7 ug h/ml.
 
Citation:  J. Agricultural and Food Chemistry 45:454-458
 
Link:  http://pubs.acs.org/cgi-bin/abstract.cgi/jafcau/1997/45/i02/abs/jf9604605.html  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Organic-Carotenoid
 
t1/2-detail:  34.8 h est
 
Wt gm-detail:  300 g
 
Water temp (°C)-detail:  20+/-0.5 C
 
Dosage-detail:  100 ug 5% water-sol beadlets in meal-sd
 
Method:  HPLC
 
Authors-red:  Gobantes I, Choubert G, Laurentie M, Milicua JCG, Gomez R
 
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