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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Detection of oxytetracycline residues in fish tissues using a sensitive bioassay.
 
Authors:  Kusser WC, Newman SG
 
Drug:  Oxytetracycline
 
Fish species:  Salmon, coho
 
Date:  1990
 
t1/2-hr:  288
 
est:  est
 
Sample:  muscle
 
Ave Weight (gm):  1000
 
Ave Water temp (°C):  12
 
Water:  Saltwater
 
Dosage:  100 mg/kg 21d
 
Route:  PO
 
Comments:  Comparison between HPLC and micro methods showed micro method able to detect to 0.1 ppm in muscle. Residues by HPLC - 0d=1.06, d8=0.59, 12d=0.2, 17d=0.18, 23d=0.07, 29d=0.13, 32d=0.06, 37d=0.04, 40d=0.03, 47d=0.06, 51d=0.03, 55d=0.04, 64d=0.17, 69d=0.06, 73,79,84,90d=nd ppm. Micro method detected levels through day 23.
 
Citation:  J. Fish Diseases 13:545-548
 
Link:  http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2761.1990.tb00816.x/abstract;jsessionid=823543DDA79241AFA6621EBC8E0FA17A.d03t03  Opens a new window
 
Genus Species:  Oncorhynchus kisutch
 
Drug Class:  Antibiotic-Tetracycline
 
t1/2-detail:  less than 12 d
 
Wt gm-detail:  1000 g
 
Water temp (°C)-detail:  12.3+/-2°C
 
Dosage-detail:  100 mg/kg 21d
 
Method:  HPLC, Micro
 
Authors-red:  Kusser WC, Newman SG
 
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