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U.S. Department of Health and Human Services

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Title:  Residues of [14C]-malachite green in eggs and fry of rainbow trout, Oncorhynchus mykiss (Walbaum), after treatment of eggs.
 
Authors:  Meinertz JR, Stehly GR, Gingerich WH, Allen JL
 
Drug:  Malachite green
 
Fish species:  Trout, rainbow
 
Date:  1995
 
t1/2-hr:  320
 
Sample:  whole body
 
Ave Weight (gm):  0.11
 
Ave Water temp (°C):  12
 
Water:  Freshwater
 
Dosage:  1.0 ug/ml every 3 days for 32d
 
Route:  BATH
 
Comments:  [14C] methano-malachite geen chloride. Residue 0.49 ug/g. in fry sampled immediately after last treatment. Residues declined over 28 d depletion to 0.055ug/g. Approx 25% depletion was due to growth from 0.08 gm-0.14 gm during the 28 d.
 
Metabolites:  Leucomalachite green, unknown polar metabolite
 
Citation:  J. Fish Diseases 18:239-247
 
Link:  none  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Organic-Dye
 
t1/2-detail:  9.7 d for MG, 13.3 d for absolute amount
 
Wt gm-detail:  0.08 g day 32, 0.14 d 59
 
Water temp (°C)-detail:  12 C
 
Dosage-detail:  1.0 ug/ml every 3 days for 32d
 
Method:  HPLC-Rad
 
Authors-red:  Meinertz JR, Stehly GR, Gingerich WH, Allen JL
 
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