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U.S. Department of Health and Human Services

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Title:  Bioavailability of oxytetracycline in sea bass, Dicentrarchus labrax (L.).
 
Authors:  Rigos G, Nengas I, Alexis M, Athanassopoulou F
 
Drug:  Oxytetracycline
 
Fish species:  Seabass, European
 
Date:  2004
 
t1/2-hr:  21
 
Sample:  blood, plasma
 
Ave Weight (gm):  120
 
Ave Water temp (°C):  22
 
Water:  Saltwater
 
Dosage:  50 mg/kg sd
 
Route:  PO
 
Comments:  AUC calculated 143 ug/hr/ml. Bioavailability 22% Residue peak at 24 h = 2.64, 48 h= 1.16, 72 h= 1.05, 96 h= 0.34, 120 h = 0.10 ug/ml.
 
Citation:  J. Fish Diseases 27:119-122
 
Link:  http://www.blackwell-synergy.com/doi/abs/10.1046/j.1365-2761.2003.00510.x  Opens a new window
 
Genus Species:  Dicentrarchus labrax
 
Drug Class:  Antibiotic-Tetracycline
 
t1/2-detail:  21 h
 
Wt gm-detail:  120+/-10 g
 
Water temp (°C)-detail:  22+/-1°C
 
Dosage-detail:  50 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Rigos G, Nengas I, Alexis M, Athanassopoulou F
 
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