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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Turnover and urinary excretion of free and acylated m.s. 222 by Rainbow trout, Salmo gairdneri.
 
Authors:  Hunn JB, Schoettger RA, Willford WA
 
Drug:  MS-222
 
Fish species:  Trout, rainbow
 
Date:  1968
 
Sample:  blood
 
Ave Weight (gm):  483
 
Ave Water temp (°C):  12
 
Water:  Freshwater
 
Dosage:  100 mg/l
 
Route:  BATH
 
Comments:  At 0 h post anesthesia, the mean concentration of free ms 222 in whole blood=73 mg/l. The acetylated concentration was 1.8 mg/l. Acetylated ms-222 accounted for 77-96% of ms-222 excreted renally. The blood and urine were cleared of both forms of the drug in 8 and 24 h respectively.
 
Citation:  J. Fisheries Research Board of Canada 25:1: 25-31
 
Link:  none  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Anesthetic-Tricaine
 
Wt gm-detail:  305-660 g
 
Water temp (°C)-detail:  12C
 
Method:  Absorbance-Bratton&Marshall
 
Authors-red:  Hunn JB, Schoettger RA, Willford WA
 
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