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Title:
Blood concentrations of tricaine methane sulphonate in Brook trout, Salvelinus fontinalis, during anesthetization, branchial irrigation, and recovery.
Authors:
Houston AH, Woods RJ (1972)
Drug:
MS-222
Fish species:
Trout, brook
Date:
1972
t1/2-hr:
2
est:
est
Sample:
blood
Ave Weight (gm):
415
Ave Water temp (°C):
4
Water:
Freshwater
Dosage:
100 mg/l
Route:
BATH
Comments:
Tricaine methane sulphonate. Blood levels (mg/l) = approx 55 during induction using 100 mg/l solution. Maintenance at 50 mg/l for 15 min = blood level of 67 mg/l, at 100 mg/l = blood level of 114 mg/l. Equilibrium when transferred to recovery 25 mg/l. Clearance blood levels (mg/l) 1 hr = 16.7, 2 hr = 6.2, 3 hr = 6.2, 6 hr= 4.5, 612hr = 4.3, 24 hr = 4.1.
Cl:
50% Cl=20 min. 90% Cl=55 min
Citation:
J. Fisheries Research Board of Canada 29:9:1344-1346.
Link:
none
Genus Species:
Salvelinus fontinalis
Drug Class:
Anesthetic-Tricaine
t1/2-detail:
< 2 hr
Wt gm-detail:
366.4-465.9
Water temp (°C)-detail:
3.5-5 C
Dosage-detail:
100 mg/l
Method:
Absorbance-Bratton&Marshall
Authors-red:
Houston AH, Woods RJ (1972)
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