Quick Links: Skip to main page content Skip to Search Skip to Topics Menu Skip to Common Links
  • Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

PhishPharm - Detail
  • Print
  • Share
  • E-mail
-
 
Title:  Uptake, metabolism, and elimination of 14C-labeled 1,2,4-trichlorobenze in rainbow trout and carp.
 
Authors:  Melancon MJ, Lech JJ
 
Drug:  TCB-(1,2,4-Trichlorobenzene)
 
Fish species:  Trout, rainbow
 
Date:  1980
 
Sample:  intestinal tract-bile
 
Ave Weight (gm):  55
 
Ave Water temp (°C):  12
 
Water:  Freshwater
 
Dosage:  0.26 mg/l 24 hr
 
Route:  BATH
 
Comments:  Before TCB dose, fish injected IP with 100 mg/kg B-naphthoflavone, or B-naphthoflavone in corn oil (100 mg/ml), TCB-(1,2,4-Trichlorobenzene)(14C). Induced fish had 90% polar metabolites vs uninduced at 60%.
 
Metabolites:  Unidentified polar metabolite
 
Citation:  J. Toxicology and Environmental Health 6:645-658
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7420471&dopt=Abstract  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Organic-Chlorinated-Pesticide
 
Wt gm-detail:  55
 
Water temp (°C)-detail:  12 C
 
Dosage-detail:  0.26 mg/l 24 hr
 
Method:  Rad
 
Authors-red:  Melancon MJ, Lech JJ
 
-
-