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U.S. Department of Health and Human Services

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Title:  Absorption and Excretion of Cefquinome in Coho Salmon (Oncorhynchus kisutch) in Freshwater at 10°C
 
Authors:  San Martin BN, Bataglia J, Hernandez P, Quiroz A, Canon H
 
Drug:  Cefquinome
 
Fish species:  Salmon, coho
 
Date:  1998
 
t1/2-hr:  119
 
Sample:  kidney
 
Ave Weight (gm):  100
 
Ave Water temp (°C):  10
 
Water:  Freshwater
 
Dosage:  20 mg/kg sd
 
Route:  IP
 
Comments:  Fish were anaesthetized prior to dosing with 1 mg/l MS-222. Cmax=29.01 ug/g. Tmax=0.5h. AUC=1,109,980. Residues0.5h=29.0, 2h=25.6, 6h=21.7, 12h=19.3, 24h=14.4, 48h=3.5, 72h=2.9, 7d=0.9, 14d=0.3, 30d=0.0. Withdrawl time based on 99.9% elimination.
 
Citation:  J. Vet. Med. A 45,615-637
 
Dep-time:  861 h
 
Link:  http://www.ncbi.nlm.nih.gov/pubmed/9923144  Opens a new window
 
Genus Species:  Oncorhynchus kisutch
 
Drug Class:  Antibiotic-Cephalosporin
 
t1/2-detail:  119.48
 
Wt gm-detail:  100 +/- 5
 
Water temp (°C)-detail:  10 +/- 0.3 C
 
Dosage-detail:  0.8 ug/L Cobactan (R )corresponding to 20 mg/kg - SD
 
Method:  Micro
 
Authors-red:  San Martin BN, Bataglia J, Hernandez P, Quiroz A, Canon H
 
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