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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Enrofloxacin pharmacokinetics in the European cuttlefish, Sepia officinalis, after a single i.v. injection and bath administration.
 
Authors:  Gore SR, Harms CA, Kukanich B, Forsythe J, Lewbart GA, Papich MG
 
Drug:  Enrofloxacin
 
Fish species:  Cuttlefish, European common
 
Date:  2005
 
Sample:  blood, hemolymph
 
Ave Weight (gm):  110
 
Ave Water temp (°C):  25
 
Water:  Saltwater
 
Dosage:  5 mg/kg sd
 
Route:  IV
 
Comments:  Cipro metabolite was not found. Salinity 32% Hemolymph sampling -one animal sacriced 0. 5 hr post dosing 8.87 ug/mL, the other 1h post dosing= 15.80 ug/ml - Hemolymph from brachial heart.
 
Metabolites:  Ciprofloxacin
 
Citation:  J. Veterinary Pharmacology and Therapeutics 28:433-439
 
Link:  http://dx.doi.org/10.1111/j.1365-2885.2005.00684.x  Opens a new window
 
Genus Species:  Sepia officinalis
 
Drug Class:  Antibiotic-Quinolone
 
Wt gm-detail:  102.9 and 117.3 g
 
Water temp (°C)-detail:  25 C
 
Dosage-detail:  5 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Gore SR, Harms CA, Kukanich B, Forsythe J, Lewbart GA, Papich MG
 
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