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U.S. Department of Health and Human Services

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Title:  The pharmacokinetics of sulfachlorpyridazine in channel catfish, Ictalurus punctatus.
 
Authors:  Alavi FK, Rolf LL, Clarke CR
 
Drug:  Sulfachlorpyridazine
 
Fish species:  Catfish, channel
 
Date:  1993
 
t1/2-hr:  5
 
Sample:  blood, plasma
 
Ave Weight (gm):  312
 
Ave Water temp (°C):  22
 
Water:  Freshwater
 
Dosage:  60 mg/kg sd
 
Route:  IC
 
Comments:  conc went from approx 1100 ug/ml to 80 in first 200 min and down to 20 by 1h.
 
Protein binding:  4.63-14.20%
 
Cl:  0.077 L/kg/h
 
Vd:  0.043 L/kg
 
Citation:  J. Veterinary Pharmacology and Therapeutics 16:232-236
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8345573&dopt=Abstract  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  230+/-65 min
 
Wt gm-detail:  312+/-220g
 
Water temp (°C)-detail:  22+/-2C
 
Dosage-detail:  60 mg/kg sd
 
Method:  Absorbance-Bratton&Marshall
 
Authors-red:  Alavi FK, Rolf LL, Clarke CR
 
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