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Title:
Absolute oral bioavailability and residues of florenicol in rainbow trout (Onchorynchus mykiss).
Authors:
Pinault LP, Millot LK, Sanders PJ
Drug:
Florfenicol
Fish species:
Trout, rainbow
Date:
1997
Sample:
blood, plasma
Ave Water temp (°C):
10
Water:
Freshwater
Dosage:
10 mg/kg sd
Route:
PO
Comments:
Fish received 1.1 mg (at 8.4 mg/kg) this their weight is presumed to be aprox 130 gm. AUC ug/h.ml=21.1, MRT=21.1h, T max =12 h, Cmax=3.23 ug/ml, Bioaval=81%.
Metabolites:
Florfenicol amine
Citation:
J. Veterinary Pharmacology and Therapeutics 20 (supp 1):297-317.
Dep-time:
80 deg day
Link:
http://agris.fao.org/agris-search/search/display.do?f=1998%2FGB%2FGB98010.xml%3BGB1997029686
Genus Species:
Oncorhynchus mykiss
Drug Class:
Antibiotic-Phenicol
Wt gm-detail:
130 g*
Water temp (°C)-detail:
10 +/- 1C
Dosage-detail:
10 mg/kg sd
Method:
HPLC
Authors-red:
Pinault LP, Millot LK, Sanders PJ
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