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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Single-dose pharmacokinetics of flumequine in the eel (Anguilla anguilla) after intravascular, oral, and bath administration.
 
Authors:  Hansen MK, Horsberg TE (2000b)
 
Drug:  Flumequine
 
Fish species:  Eel, European
 
Date:  2000
 
t1/2-hr:  126
 
est:  est
 
Sample:  blood, plasma
 
Ave Weight (gm):  183
 
Ave Water temp (°C):  23
 
Water:  Freshwater
 
Dosage:  40 mg/L sd 2 hr
 
Route:  BATH
 
Comments:  t1/2 estimated from graph. 2 hour large scale commercial bath treatment bioavailability=35% (pH drops with more CO2)
 
Citation:  J. Veterinary Pharmacology and Therapeutics 23:169-174
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11110105&dopt=Abstract  Opens a new window
 
Genus Species:  Anguilla anguilla
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  126 h
 
Wt gm-detail:  183 +/-26g(mean + SD)
 
Water temp (°C)-detail:  23 +/- 0.3
 
Dosage-detail:  40 mg/L sd 2 hr
 
Method:  HPLC
 
Authors-red:  Hansen MK, Horsberg TE (2000b)
 
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