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U.S. Department of Health and Human Services

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Title:  Metabolism and residue depletion of albendazole in rainbow trout, tilapia, and Atlantic salmon after oral administration.
 
Authors:  Shaikh B, Rummel N, Gieseker C, Serfling S, Reimschuessel R
 
Drug:  Albendazole
 
Fish species:  Tilapia (hybrid)
 
Date:  2003
 
t1/2-hr:  40
 
est:  est
 
Sample:  muscle+skin
 
Ave Weight (gm):  434
 
Ave Water temp (°C):  24
 
Water:  Freshwater
 
Dosage:  10 mg/kg sd
 
Route:  PO
 
Comments:  Metabolite: Peak at 8 hr, 55 ug/kg - range 10-88. Average residues at 4h=30, 8h=55, 12h=51, 24h=32, 48h= 2, 72/96/144h = nd. Only one fish had residues at 120 h.
 
Metabolites:  ABZ-SO
 
Citation:  J. Veterinary Pharmacology and Therapeutics 26:421-428
 
Link:  http://onlinelibrary.wiley.com/doi/10.1046/j.0140-7783.2003.00534.x/abstract  Opens a new window
 
Genus Species:  Oreochromis niloticus niloticus x Oreochromis mossambicus (hybrid)
 
Drug Class:  Antiparasitic-Benzimidazole
 
t1/2-detail:  40 h est
 
Wt gm-detail:  2 groups: 254+/-54g and 613+/-126 g
 
Water temp (°C)-detail:  25+/-2 C
 
Dosage-detail:  10 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Shaikh B, Rummel N, Gieseker C, Serfling S, Reimschuessel R
 
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