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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Preliminary study on the kinetics of Oxytetracycline in shellfish exposed to an effluent of a land-based fish farm: experimental approach.
 
Authors:  Le Bris H, Pouliquen H, Debernardi JM, Buchet V, Pinault L
 
Drug:  Oxytetracycline
 
Fish species:  Clam, short-necked
 
Date:  1995
 
Sample:  whole body
 
Ave Weight (gm):  75
 
Ave Water temp (°C):  15
 
Water:  Saltwater
 
Dosage:  45 g 7 d sediment system*
 
Route:  BATH
 
Comments:  Simulated effluent tank system (sediment water pumped to other tanks). Concentration OTC in sediment = 3.5 ug/g (estimated) Concentration OTC in seawater = 1.5 ug/g (estimated) peak concentration in tissues = 0.5 ug/g (estimated at near 3 days - stayed near that level for the 7 day treatment and 14 day depletion - near 0.3 by 14 depletion.
 
Citation:  Marine Environmental Research 40:171-180
 
Link:  http://dx.doi.org/10.1016/0141-1136(94)00009-E  Opens a new window
 
Genus Species:  Ruditapes phillippinarum
 
Drug Class:  Antibiotic-Tetracycline
 
Wt gm-detail:  75+/-1g
 
Water temp (°C)-detail:  15
 
Dosage-detail:  sediment dosed tanks, OTC in sediment = 3.5 ug/g, seawater = 1.5 ug/g.
 
Method:  HPLC
 
Authors-red:  Le Bris H, Pouliquen H, Debernardi JM, Buchet V, Pinault L
 
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