Quick Links: Skip to main page content Skip to Search Skip to Topics Menu Skip to Common Links
  • Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

PhishPharm - Detail
  • Print
  • Share
  • E-mail
-
 
Title:  Use of aquatic organisms as models to determine the in vivo contribution of flavin-containing monooxygenases in xenobiotic biotransformation.
 
Authors:  Schlenk D
 
Drug:  Aldicarb
 
Fish species:  Catfish, channel
 
Date:  1995
 
t1/2-hr:  140
 
Sample:  whole body
 
Water:  Freshwater
 
Dosage:  10 mg/kg sd
 
Route:  IP
 
Comments:  Catfish are more tolerant of the toxicity (vs trout). T 1/2 alpha=16.4, beta=140 vs trout values of T 1/2 alpha=3h, beta=28h (but trout received 1 mg/kg IP vs 10 mg/kg that catfish received).
 
Metabolites:  Sulfone
 
Citation:  Molecular Marine Biology and Biotechnology4:4:323-330
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8541983&itool=iconabstr  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Carbamate-Pesticide
 
t1/2-detail:  T 1/2 alpha=16.4, beta=140
 
Wt gm-detail:  Not specified
 
Water temp (°C)-detail:  Not specified
 
Dosage-detail:  10 mg/kg sd
 
Method:  Rad
 
Authors-red:  Schlenk D
 
-
-