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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Oxytetracycline residues in different tissues of trout.
 
Authors:  Herman RL, Collis D, Bullock GL
 
Drug:  Oxytetracycline
 
Fish species:  Trout, sea (brown)
 
Date:  1969
 
t1/2-hr:  312
 
est:  est
 
Sample:  muscle
 
Ave Weight (gm):  227
 
Ave Water temp (°C):  7
 
Water:  Freshwater
 
Dosage:  75 mg/kg for 14d
 
Route:  PO
 
Comments:  Residues from graph: 3d= 0.68, 7d= 0.82, 14d= 0.63 mg/kg. Post treatment residues : 3d= 0.4, 6d=0.45, 10d= 0.7, 13d=0.25, 15d= 0.3, 21d= 0.25 mg/kg, nd after 28d. Muscle residues were reduced or destroyed by cooking. Ave C max 0.8 mg/kg 7d dosing, 2nd peak 0.6 10 d withdrawal.Highest individual Cmax =1.375 ppm. T1/2 est from graph.
 
Citation:  Technical Papers of the Bureau of Sport Fisheries and Wildlife #37:3-6
 
Dep-time:  4 weeks
 
Link:  none  Opens a new window
 
Genus Species:  Salmo trutta trutta
 
Drug Class:  Antibiotic-Tetracycline
 
Wt gm-detail:  227g
 
Water temp (°C)-detail:  6-7 C
 
Dosage-detail:  75 mg/Kg 14d. Terramycin or TM -50.
 
Method:  Micro
 
Authors-red:  Herman RL, Collis D, Bullock GL
 
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