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PhishPharm - Detail
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Title:
A physiologically based pharmacokinetic and pharmacodynamic model for paraoxon in rainbow trout.
Authors:
Abbas R, Hayton WL
Drug:
Paraoxon
Fish species:
Trout, rainbow
Date:
1997
Sample:
brain
Ave Weight (gm):
120
Ave Water temp (°C):
12
Water:
Freshwater
Dosage:
75 ng/ml 5 d
Route:
BATH
Comments:
Residues peaked by 24 hrs with a plateau at approx 400 ng/m remaining constant during the rest of the 140 hr exposure.
Citation:
Toxicology and Applied Pharmacology 145:192-201
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9221837
Genus Species:
Oncorhynchus mykiss
Drug Class:
Organic-Phosphorus-Pesticide
t1/2-detail:
>25 h
Wt gm-detail:
100-140 g
Water temp (°C)-detail:
12 C
Dosage-detail:
75 ng/ml for 5 d
Method:
Absorbance
Authors-red:
Abbas R, Hayton WL
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