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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  A physiologically based pharmacokinetic and pharmacodynamic model for paraoxon in rainbow trout.
 
Authors:  Abbas R, Hayton WL
 
Drug:  Paraoxon
 
Fish species:  Trout, rainbow
 
Date:  1997
 
Sample:  heart
 
Ave Weight (gm):  120
 
Ave Water temp (°C):  12
 
Water:  Freshwater
 
Dosage:  75 ng/ml 5 d
 
Route:  BATH
 
Comments:  Residues peaked by 24 hrs with a plateau at approx 400 ng/m remaining constant during the rest of the 140 hr exposure.
 
Citation:  Toxicology and Applied Pharmacology 145:192-201
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9221837  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Organic-Phosphorus-Pesticide
 
t1/2-detail:  >25 h
 
Wt gm-detail:  100-140 g
 
Water temp (°C)-detail:  12 C
 
Dosage-detail:  75 ng/ml for 5 d
 
Method:  Absorbance
 
Authors-red:  Abbas R, Hayton WL
 
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