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U.S. Department of Health and Human Services

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Title:  Sulfadimethoxine pharmacokinetics and metabolism in the channel catfish (Ictalurus punctatus).
 
Authors:  Squibb KS, Michel CMF, Zelikoff JT OConnor JM
 
Drug:  Sulfadimethoxine
 
Fish species:  Catfish, channel
 
Date:  1988
 
t1/2-hr:  13
 
Sample:  blood
 
Ave Weight (gm):  500
 
Ave Water temp (°C):  0
 
Water:  Freshwater
 
Dosage:  40 mg/kg sd
 
Route:  IV
 
Comments:  Sulfadimethoxine (14C or 35S)
 
Protein binding:  18.4 +/- 2.5%
 
Vd:  0.66 L/kg
 
Metabolites:  N-A-SDM, small amount of glucuronides and sulfates
 
Citation:  Veterinary and Human Toxicology 30 (supp 1):31-35
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3212940&dopt=Abstract  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  12.8h
 
Wt gm-detail:  400-600 g
 
Water temp (°C)-detail:  Not Specified
 
Dosage-detail:  40 mg/kg sd
 
Method:  Rad
 
Authors-red:  Squibb KS, Michel CMF, Zelikoff JT OConnor JM
 
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