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U.S. Department of Health and Human Services

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Title:  Pharmacokinetics and metabolism of fenbendazole in channel catfish.
 
Authors:  Kitzman JV, Holley JH, Huber WG, Koritz GD, Davis LE, Neff-Davis CA, Bevill RF, Short CR, Barker SA, Hsieh LC
 
Drug:  Fenbendazole
 
Fish species:  Catfish, channel
 
Date:  1990
 
t1/2-hr:  17
 
Sample:  blood, plasma
 
Ave Weight (gm):  1000
 
Ave Water temp (°C):  22
 
Water:  Freshwater
 
Dosage:  1 mg/kg sd
 
Route:  IVC
 
Comments:  Vd= 1.45 +/- 0.33 L/kg (area), Vd= 1.23 +/- 0.14 L/kg (steady state)
 
Cl:  0.0598 L/kg/h
 
Vd:  1.23 +/- 0.14 L/kg
 
Citation:  Veterinary Research Communications 14:217-226
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2382406&dopt=Abstract  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Antiparasitic-Benzimidazole
 
t1/2-detail:  16.8 h
 
Wt gm-detail:  1.07 +/- 0.12 kg
 
Water temp (°C)-detail:  22 +/- 1 C
 
Dosage-detail:  1 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Kitzman JV, Holley JH, Huber WG, Koritz GD, Davis LE, Neff-Davis CA, Bevill RF, Short CR, Barker SA, Hsieh LC
 
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