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U.S. Department of Health and Human Services

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Title:  Absorption, tissue distribution, metabolism and excretion of ormetoprim and sulphadimethoxine in Atlantic salmon (Salmo salar) after intravenous and oral administration of Romet-30.
 
Authors:  Samuelsen OB, Ervik A, Wennevik V
 
Drug:  Sulfadimethoxine
 
Fish species:  Salmon, Atlantic
 
Date:  1995
 
t1/2-hr:  12
 
est:  est
 
Sample:  muscle
 
Ave Weight (gm):  525
 
Ave Water temp (°C):  10
 
Water:  Saltwater
 
Dosage:  5/25 OMP/SDM mg/kg sd
 
Route:  PO
 
Comments:  After 24 h= 5.93 +/- 3.69 µg/g, after 36h= 2.83 +/- 1.53, after 48h= 0.96 +/- 1.17, after 72h= 0.32 +/- 0.10. (Romet-30)
 
Citation:  Xenobiotica 25:1169-1180
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8592867&dopt=Abstract  Opens a new window
 
Genus Species:  Salmo salar
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  12 h (est)
 
Wt gm-detail:  450-600 g
 
Water temp (°C)-detail:  10 +/- 0.5 C
 
Dosage-detail:  25 mg/kg SDM and 5 mg/kg OMP (Romet-30) sd
 
Method:  HPLC
 
Authors-red:  Samuelsen OB, Ervik A, Wennevik V
 
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