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U.S. Department of Health and Human Services

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Title:  Pharmacokinetics, tissue distribution and metabolism of acriflavine and proflavine in the channel catfish (Ictalurus punctatus).
 
Authors:  Plakas SM, El Said KR, Bencsath FA, Musser SM, Hayton WL
 
Drug:  Proflavine
 
Fish species:  Catfish, channel
 
Date:  1998
 
t1/2-hr:  9
 
Sample:  blood, plasma
 
Ave Weight (gm):  620
 
Ave Water temp (°C):  24
 
Water:  Freshwater
 
Dosage:  1.0 mg/kg sd
 
Route:  IVC
 
Comments:  Residue 24 h= 0.036 ug/g.
 
Cl:  4.58 L/kg/h
 
Vd:  47.0 L/kg
 
Citation:  Xenobiotica 28:6:605-616
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9667083&dopt=Abstract  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Organic-Dye
 
t1/2-detail:  8.71 h
 
Wt gm-detail:  0.62 kg
 
Water temp (°C)-detail:  24 C
 
Dosage-detail:  1.0 mg/kg sd
 
Method:  HPLC-Rad, HPLC/MS
 
Authors-red:  Plakas SM, El Said KR, Bencsath FA, Musser SM, Hayton WL
 
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