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Title:
In vivo and in vitro renal metabolism and excretion of benzoic acid by a marine teleost, the southern flounder.
Authors:
James MO, Pritchard, JB
Drug:
Benzoic acid
Fish species:
Flounder, southern
Date:
1987
Sample:
urine
Ave Weight (gm):
550
Ave Water temp (°C):
0
Water:
Saltwater
Dosage:
0.25 mmol/kg 10uCi (15 mg total single dose)
Route:
IM
Comments:
Increasing excretion for 5 days after IM dose. Held in flowing seawater in Marineland Florida
Metabolites:
Benzoyltaurine
Citation:
American Society for Pharmacology and Experimental Therapeutics 15:5:665-670
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2891484&dopt=Abstract
Genus Species:
Paralichthys lethostigma
Drug Class:
Antifungal-Benzoic acid
Wt gm-detail:
300-800g
Water temp (°C)-detail:
Not Specified
Dosage-detail:
0.25 mmol/kg 10uCi (15 mg total single dose)
Method:
Rad
Authors-red:
James MO, Pritchard, JB
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