Quick Links: Skip to main page content
Skip to Search
Skip to Topics Menu
Skip to Common Links
U.S. Food & Drug Administration
Follow FDA
En Español
Search FDA
Home
Food
Drugs
Medical Devices
Radiation-Emitting Products
Vaccines, Blood & Biologics
Animal & Veterinary
Cosmetics
Tobacco Products
PhishPharm - Detail
FDA Home
PhishPharm
Detail
-
Please note:
JavaScript must be enabled for this application to work properly.
Check your settings
if you are unsure if your JavaScript is enabled.
Title:
Comparative single-dose pharmacokinetics of four quinolones, oxolinic acid, flumequine, sarafloxacin, and enrofloxacin in Atlantic salmon (Salmo salar) held in seawater at 10 oC.
Authors:
Martinsen B, Horsberg TE
Drug:
Oxolinic acid
Fish species:
Salmon, Atlantic
Date:
1995
t1/2-hr:
18
Sample:
blood, plasma
Ave Weight (gm):
240
Ave Water temp (°C):
10
Water:
Saltwater
Dosage:
25 mg/kg sd
Route:
IV
Comments:
Residues 3 h= 5.2, 6 h= 3.54, 12 h= 2.22, 24 h= 1.01, 48 h= 0.34, 72 h= 0.26, 120 h= 0.02 ug/g.
Cl:
0.28 L/kg/h
Vd:
5.4 L/kg
Citation:
Antimicrobial Agents and Chemotherapy 39:1059-1064
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7625789&dopt=Abstract
Genus Species:
Salmo salar
Drug Class:
Antibiotic-Quinolone
t1/2-detail:
18.2 h
Wt gm-detail:
240 +/- 50 g
Water temp (°C)-detail:
10.2 +/- 0.2 C
Dosage-detail:
25 mg/kg sd
Method:
HPLC
Authors-red:
Martinsen B, Horsberg TE
-
-